The Houston Astros scored two runs in the 10th inning on Hunter Gaddis’ wild pitch and a RBI single by Isaac Paredes to defeat the host Cleveland Guardians 5-3 on Saturday.

The Astros took their second straight in the three-game weekend series and got a home run from Yainer Diaz.

Jose Ramirez homered for the Guardians, who have dropped four of their last five.

Josh Hader (2-0) pitched a scoreless ninth inning to get the win and Bennett Sousa worked the 10th for his first save of the season and second of his career. Gaddis (0-1) took the loss.

Ramirez’ two-run homer in the seventh tied the game at 3. He lined Shawn Dubin’s 3-1 changeup down the right-field line and just over the fence for Ramirez’s 12th home run. He also stretched his career-high, on-base streak to 33 games.

Astros’ starter Hunter Brown allowed a run and four hits in 5 1/3 innings, walking a season-high five and striking out nine.

He gave up Gabriel Arias’ RBI single in the sixth and left with the bases loaded and one out with Houston leading 3-1. Lefthander Steven Okert came in and struck out pinch hitter David Fry and Will Wilson to end the inning.

Cleveland starter Gavin Williams gave up three runs on five hits in six innings with two walks and five strikeouts.

Jeremy Pena’s two-out infield single in the fifth gave the Astros a 1-0 lead. It came after Williams struck out Mauricio Dubon and Brendan Rodgers with runners on second and third.

Diaz’ two-run homer with two outs in the sixth made it 3-0. He lofted Williams’ 3-2 back-up slider down the left-field line and into the stands for Diaz’s eighth home run. It scored Victor Caratini, who had walked with two out, ahead of Diaz.

Brown and Williams each allowed only one hit through the first four innings.

Brown got out of a two on, two out situation in the first by striking out Daniel Schneemann, one of his five strikeouts in the first two innings.